RESULTS PUBLISHED IN NATURE BIOTECH
- urteglibauskaite
- Jul 9, 2020
- 1 min read
Updated: Mar 19
In the September issue of Nature Biotechnology, we shared our research describing the specificity of natural and engineered CRISPR nucleases. We showcased our newly-developed "next-generation" biochemistry method - NucleaSeq - that captures nuclease kinetics and cleavage outcomes at nucleotide-resolution. The data and models presented in this publication help genome engineers select a nuclease that matches their goals and predict its activity.
This work was made possible through inter-disciplinary collaborations with the Finkelstein, Press and Doudna labs.